Table 1.
Spearman correlation coefficients and p-values of the correlations of BMI and laboratory parameters and chemerin in the whole cohort before direct-acting antiviral (DAA) therapy, at 4 and 12 weeks after start of therapy and 3 months after the end of therapy. Significant correlations are in bold.
| Parameter | Baseline (82 patients) |
4 weeks (79 patients) |
12 weeks (81 patients) |
3 Months after End of Therapy (71 patients) |
|---|---|---|---|---|
| BMI kg/m2 | 0.046 (0.695) | 0.028 (0.816) | 0.054 (0.653) | −0.002 (0.987) |
| MELD Score | −0.777 (<0.001) | −0.749 (<0.001) | −0.752 (<0.001) | −0.578 (<0.001) |
| ALT U/L | 0.119 (0.286) | −0.067 (0.559) | −0.057 (0.612) | 0.198 (0.104) |
| AST U/L | −0.233 (0.035) | −0.379 (0.001) | −0.500 (<0.001) | −0.475 (<0.002) |
| Bilirubin mg/dL | −0.588 (<0.001) | −0.614 (<0.001) | −0.668 (<0.001) | −0.591 (<0.001) |
| Albumin g/L | 0.592 (<0.001) | 0.453 (<0.001) | 0.537 (<0.001) | 0.220 (0.071) |
| INR | −0.815 (<0.001) | −0.744 (<0.001) | −0.786 (<0.001) | −0.815 (<0.001) |
| Creatinine mg/dL | 0.099 (0.378) | 0.000 (0.997) | 0.111 (0.325) | 0.165 (0.175) |
| Leukocytes n/L | 0.628 (<0.001) | 0.515 (<0.001) | 0.572 (<0.001) | 0.360 (0.003) |
| CRP mg/L | 0.003 (0.979) | 0.079 (0.489) | −0.103 (0.362) | 0.199 (0.101) |
| HDL mg/dL | 0.021 (0.857) | 0.123 (0.292) | 0.129 (0.261) | 0.005 (0.971) |
| LDL mg/dL | 0.598 (<0.001) | 0.655 (<0.001) | 0.681 (<0.001) | 0.618 (<0.001) |
Alanine amino transferase, ALT; aspartate aminotransferase, AST; C-reactive protein, CRP; MELD, model of end-stage liver disease; INR, international normalized ratio; LDL, low-density lipoprotein; HDL, high-density lipoprotein.