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The types of redox-sensitive Cys modification in protein kinases.
| Type | Site | S-NO | S-SG | S-Ox | S-SH | Mechanisms |
|---|---|---|---|---|---|---|
| CaMKI | Cys179 | + | + | + | + | Inhibition with decline of Vmax |
| CaMKII | Cys6 | + | − | − | + | Inhibition with ATP competitive fashion |
| CaMKIV | Cys198 | − | − | + | + | Inhibition of phosphorylation at Thr196 |
| RSK1 | Cys223 | − | + | + | + | Inhibition with decline of Vmax |
