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Assessed factors together with their upper (+1), lower (−1) and mid-levels.
| Factors | −1 | 0 | +1 |
|---|---|---|---|
| pH (A, pH unit) | 5.0 | 7.0 | 9.0 |
| Adsorbent Dose (AD, B, mg/15 mL) | 20.0 | 50.0 | 80.0 |
| Initial Drug Concentration ([SARA], C, ppm) | 10.0 | 25.0 | 40.0 |
| Contact Time (CT, D, min.) | 10.0 | 65.5 | 120.0 |
