ROS levels and pro-inflammatory molecules in the BM and spleen. (A) ROS levels (=DHE Mean Fluorescence Intensity, MFI) in the BM, (B) ROS levels in the spleen, (C) IL-6 MFI in the BM, (D) IL-6 MFI in the spleen, (E) IFNγ+CD8+ T cells in the BM, (F) TNF+CD8+ T cells in the BM, (G) IL-2+ CD8+ T cells in the BM, (H) IFNγ+CD8+ T cells in the spleen, (I) TNF+CD8+ T cells in the spleen, (J) IL-2+ CD8+ T cells in the BM of young (white columns) and old (black columns) mice treated with PBS, NAC, Vc, or NAC+Vc. Data are shown as mean ± SEM. Two-way ANOVA, Tukey post-hoc test. * p < 0.05; ** p < 0.01; **** p < 0.0001.