Table 3.

Advantages of essential oils (EOs) and their impact on anti-acne microemulsion formulation.

No.	Advantages	Ref.
1	EOs can be selected as an oil phase in ME or combined with a second vegetable or synthetic oil.	[247]
2	EOs can be a good alternative to chemical solvents.	[248]
3	EOs act as penetration enhancers at skin site, increasing the localization of drugs.	[246]
4	EOs have low toxicity, being GRAS recognized.	[246]
5	EOs protect the API from degradation reactions, improving its stability; the microemulsification will protect EOs from degradation and volatilization.	[248,249]
6	EOs can exert self-anti-acne action on microbial species like P. acnes or S. aureus.	[250]