Table 2.
Characteristics of fetuses with aneuploidies/polyploidy detected by 750 K SNP array among the 548 fetuses with ventriculomegaly.
| No | SNP array results | Degrees of ventriculomegaly | Other ultrasound findings | Outcome |
|---|---|---|---|---|
| 1 | Trisomy 21 | Mild (bilateral) | – | TOP |
| 2 | Trisomy 21 | Moderate (bilateral) | – | TOP |
| 3 | Trisomy 21 | Mild (unilateral) | Hypoplastic nasal bone | TOP |
| 4 | Trisomy 21 | Mild (unilateral) | Hypoplastic nasal bone | TOP |
| 5 | Trisomy 21 | Mild (bilateral) | Enlarged cisterna magna, intracardiac echogenic focus | TOP |
| 6 | Trisomy 21 | Moderate (bilateral) | Intracardiac echogenic focus | TOP |
| 7 | Trisomy 21 | Moderate (bilateral) | short femur length | TOP |
| 8 | Trisomy 21 | Mild (unilateral) | Pleural effusion, fetal hydrops | TOP |
| 9 | Trisomy 21 | Mild (unilateral) | Tetralogy of Fallot, pericardial effusion | TOP |
| 10 | Trisomy 21 | Mild (unilateral) | Echogenic kidney | TOP |
| 11 | Trisomy 18 | Servere (bilateral) | – | Intrauterine fetal death |
| 12 | Trisomy 18 | Servere (bilateral) | VSD, talipes equinovarus, polyhydramnios | TOP |
| 13 | XXY | Moderate (unilateral) | short femur length | TOP |
| 14 | Triploid | Servere (unilateral) | IUGR, cervical lymphadenoma | TOP |
| 15 | Mosaic trisomy 9 | Mild (unilateral) | Cerebellar vermis hypoplasia | TOP |
| 16 | Mosaic trisomy 9 | Mild (bilateral) | C4–C5 vertebral abnormality, pyelectasis | TOP |
| 17 | Mosaic trisomy 12 | Mild (unilateral) | – | TOP |
VSD ventricular septal defect, IUGR intrauterine growth retardation, TOP termination of pregnancy.