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. 2020 Nov 27;11:6034. doi: 10.1038/s41467-020-19862-y

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© The Author(s) 2020

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Fig. 6 — qPCR quantification of hypothalamic RNA. Hcrt is largely downregulated in 5HTT^KO/KO mice as compared to WT littermates. Values are mean ± SEM, n = 3 (one-way ANOVA, genotype F (4, 11) = 64.79, P < 0.0001, followed by Dunnett’s test, **P < 0.01; ***P < 0.001). DKO: n = 3, 5HTT^KO/KO: n = 3, Hcrt^KO/KO: n = 3, 5HTT^+/KO;Hcrt^KO/KO: n = 4 and WT: n = 3.