Table 3.
Go annotation of predicted targets in tobacco-flavored e-liquid.
| Term | Count | % | p-value |
|---|---|---|---|
| Molecular function | |||
| GO:0003735 ~ structural constituent of ribosome | 28 | 3.341 | 3.99E-06 |
| GO:0016614 ~ oxidoreductase activity, acting on CH-OH group of donors | 20 | 2.387 | 1.68E-05 |
| GO:0005102 ~ receptor binding | 102 | 12.172 | 2.01E-05 |
| GO:0019838 ~ growth factor binding | 19 | 2.267 | 2.29E-05 |
| GO:0016616 ~ oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | 18 | 2.148 | 2.50E-05 |
| GO:0048037 ~ cofactor binding | 29 | 3.461 | 6.38E-05 |
| GO:0005198 ~ structural molecule activity | 61 | 7.279 | 6.94E-05 |
| GO:0050839 ~ cell adhesion molecule binding | 40 | 4.773 | 1.91E-04 |
| GO:0050840 ~ extracellular matrix binding | 10 | 1.193 | 6.37E-04 |
| GO:0072341 ~ modified amino acid binding | 11 | 1.313 | 1.31E-03 |
| Biological processes | |||
| GO:0055114 ~ oxidationreduction process | 89 | 10.621 | 1.78E-09 |
| GO:1901566 ~ organonitrogen compound biosynthetic process | 113 | 13.484 | 2.23E-09 |
| GO:0006364 ~ rRNA processing | 38 | 4.535 | 3.08E-09 |
| GO:0016072 ~ rRNA metabolic process | 38 | 4.535 | 6.25E-09 |
| GO:0006082 ~ organic acid metabolic process | 82 | 9.785 | 9.19E-09 |
| GO:0019752 ~ carboxylic acid metabolic process | 75 | 8.950 | 3.72E-08 |
| GO:0042594 ~ response to starvation | 26 | 3.103 | 3.78E-08 |
| GO:0043436 ~ oxoacid metabolic process | 75 | 8.950 | 4.80E-08 |
| GO:0009991 ~ response to extracellular stimulus | 48 | 5.728 | 6.31E-08 |
| GO:0006793 ~ phosphorus metabolic process | 202 | 24.105 | 1.03E-07 |
| Cellular component | |||
| GO:1903561 ~ extracellular vesicle | 202 | 24.105 | 4.68E-09 |
| GO:0043230 ~ extracellular organelle | 202 | 24.105 | 4.76E-09 |
| GO:0044421 ~ extracellular region part | 258 | 30.788 | 1.18E-08 |
| GO:0070062 ~ extracellular exosome | 199 | 23.747 | 1.45E-08 |
| GO:0031988 ~ membranebounded vesicle | 238 | 28.401 | 1.58E-07 |
| GO:0005829 ~ cytoso | 214 | 25.537 | 2.67E-05 |
| GO:0005576 ~ extracellular region | 278 | 33.174 | 2.82E-05 |
| GO:0031012 ~ extracellular matrix | 48 | 5.728 | 6.23E-05 |
| GO:0031967 ~ organelle envelope | 85 | 10.143 | 1.30E-04 |
| GO:0031975 ~ envelope | 85 | 10.143 | 1.52E-04 |
The top 10 most enriched GO terms are listed in terms for biological process, cellular component, and molecular function based on p-values.