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. 2020 Nov 27;11:6074. doi: 10.1038/s41467-020-19888-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — The nodes of the graph are dietary exposures (circles) and cardiovascular diseases (diamonds) as two sets of nodes. Each studied association is shown by an edge whose color denotes the “direction” (i.e., positive or negative) of the association. Green and red links indicate negative and positive associations, respectively, between an exposure and a disease. Grey links denote associations that were studied but not found to be statistically significant. In the context of NHS, CHD refers to non-fatal MI and fatal coronary heart disease; also, coronary artery disease (CAD) refers to non-fatal MI and fatal coronary artery disease. Cardiovascular disease (CVD) is defined as a composite of coronary artery disease and non-fatal or fatal stroke. Source data are provided in Source Data - Figure 1.xlsx. The figure aims to illustrate the body of work derived from NHS data on cardiovascular diseases. A detailed comparison of the result of our analysis with previous NHS-related work and other findings in the literature is provided in the section “Comparison with the literature”.