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. 2020 Nov 27;11:6074. doi: 10.1038/s41467-020-19888-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a P values are associated with two-sided Wald tests. The Y axis indicates the negative logarithm of the P value of each exposure. The dotted red horizontal line marks the level of 0.05 P value threshold and the solid red line demonstrates the level of 0.00117 P value threshold associated with the level of 0.05 FDR. Significant foods (diamonds) and nutrients (circles) with a negative association (HR < 1) are highlighted in green and exposures with a positive association (HR > 1) are shown in red. Source data are provided in Source Data - Figure 3-a.xlsx. b Bi-partite food-nutrient network, where negatively associated exposures are shown in green and positively associated exposures are shown in red. Different shapes are used to differentiate between foods (diamonds) and nutrients (circles). The node size is proportional to the absolute value of the estimated effect size. The link thickness is proportional to the amount of each nutrient’s composition in food. Source data are provided in Source Data - Figs. 3-b and 4-b.xlsx.