Table 3.

Knowledge graph data preparation.

PubMed ID	Year	Title	Abstract	Exposure	Phenotype	Gender	Association	Model	Effect size
29529162	2018	Carbohydrate quality and quantity and risk of coronary heart disease among us women and men	... We aimed to assess the relation between various measures of carbohydrate quality and incident CHD. Data on diet and lifestyle behaviors were prospectively collected on 75,020 women and 42,865 men participating in the Nurses’ Health Study (NHS) and the Health Professionals Follow-Up Study (HPFS) starting in 1984 and 1986, respectively, and every 2–4 years thereafter until 2012 ... In models adjusted for age, lifestyle behaviors, and dietary variables, the highest quintile of carbohydrate intake was not associated with incident CHD (pooled RR = 1.04; 95% CI: 0.96, 1.14; P trend = 0.31). Total fiber intake was not associated with risk of CHD (pooled RR = 0.94; 95% CI: 0.85, 1.03; P trend = 0.72), while cereal fiber was associated with a lower risk for incident CHD (pooled RR = 0.80; 95% CI: 0.74, 0.87; P trend <0.0001). In fully adjusted models, the carbohydrate-to-total fiber ratio was not associated with incident CHD (pooled RR = 1.04; 95% CI: 0.96, 1.13; P trend = 0.46). However, the carbohydrate-to-cereal fiber ratio and the starch-to-cereal fiber ratio were associated with an increased risk for incident CHD (pooled RR = 1.20; 95% CI: 1.11, 1.29; P trend <0.0001, and pooled RR = 1.17; 95% CI: 1.09, 1.27; P trend <0.0001)...59	Total fiber	CHD	Both	No association	Cox	–
				Cereal fiber	CHD	Both	Negative	Cox	0.8
				Ratio of carb to total fiber	CHD	Both	No association	Cox	–
				Ratio of carb to cereal fiber	CHD	Both	Positive	Cox	1.2