Figure 4.

Effect of staphylococcal leucocidins PVL and HlgABC on bone marrow leucocytes, represented by the proportion of intact cells after incubation with toxins on the corresponding gate. Mean ± SD of 11 bone marrows for PVL and 10 bone marrows for HlgABC. For each sub-population, the effect of staphylococcal leucocidin was assessed by comparing the proportion of intact cells after toxic challenge to the negative control without toxins (i.e., 100% of intact cells) using Student’s t-test. The effect of PVL between leucocyte sub-types was compared using Student’s t-test with Bonferroni adjustment. *, p < 0.05; **, p < 0.01; ***, p < 0.001; N.S., non-significant. Gr imm 2, granulocytic immature 2 cells; PMN, polymorphonuclear neutrophil cells; CD11b+ mo, CD11b+ monocytes; NK, natural killer; T NK, T natural killer.