Table 2.

Advantages and disadvantages of anti- and pro-oxidant therapies in cancer.

	Advantages	Disadvantages	References
Antioxidants	Antagonize excess free radicals in healthy cells	Cancers may also benefit from the use of antioxidants	[13,45,58]
	Enhancement of host antitumor immunity	Antioxidants might prevent cancers than curing them	[47,108]
	Available in a wide variety of fruits and vegetables	Difficulty in delivery to tumor mass or internal organs	[109,110]
	Short-lived and ultra-fast acting oxidizing biomolecules	Acts on DNA causing mutations and increasing cancer	[111,112,113]
Prooxidants	Increase oxidative stress hindering cancer growth	Damage healthy tissues, especially the internal organs	[23,114]
	Synergistic action with many anti-cancer drugs	Increase cytotoxicity during radiotherapy	[115,116]