Ab	Antibody
AEC	Absolute eosinophil count
AMC	Absolute monocyte count
AJCC	American Joint Committee for Cancer
AKT	Protein Kinase B
BEAMing	Beads, emulsion, amplification and magnetics
BIM	Bcl-2-like protein 11
BTLA	B-T lymphocyte attenuator
BRAF	v-Raf murine sarcoma viral oncogene homolog B1
CCR	Cytokeratin receptor
CDKN	Cyclin-Dependent Kinase Inhibitor
CDK4	Cyclin-Dependent Kinase 4
CpG	Cytosine linked to a guanine by a phosphate bond
CSD	Chronic sun damage
CSF-1	Colony-Stimulating Factor-1
CTC	Circulating tumor cells
ctDNA	Cellular tumor DNA
CTLA-4	Cyotoxic T-Lymphocyte associated protein 4
CXCL	Chemokine (C-X-C motif) ligand
DC	Dendritic cells
DFI	Disease-free survival
DNA	Desosiiribonucleic acid
ddPCR	Digital droplets polymerase chain reaction
EpCAM	Epithelial cell adhesion
Fn	Fusobacterium nucleatum
FOXP3	Forkhead box P3
GNAQ	G protein subunit alpha q
GNA11	Guanine nucleotide-binding protein subunit alpha-11
HLA	Human leukocyte antigen
ICIs	Immune checkpoint inhibitors
IFN	Interferon
IHC	Immunohistochemistry
IL-12	Interleukin
KIT	Proto-oncogene receptor tyrosine kinase
LAG-3	Lymphocyte-activation gene 3
LDH	Lactate dehydrogenase
MAPK	Mitogen-activated protein kinases
MDSC	Myeloid-derived suppressor cell
MET	MET proto-oncogene
MIA	Melanoma inhibitory activity
miRNA	Microrna
MITF	Melanocyte inducing transcription factor
MSS	Melanoma-specific survival
mTOR	Mammalian target of rapamycin
NF1	Neurofibromin 1
NGS	Next-generation sequencing
NK	Natural killer
NRAS	Neuroblastoma RAS Viral Oncogene Homolog
NSCLC	Non-small cell lung cancer
ORR	Overall response rate
OS	Overall survival
PD-L1	Programmed Death—Ligand 1
PCR	Polymerase chain reaction
PFS	Progression Free Survival
PI3K	Phosphatidyl inositol 3 kinases
PKC	Protein kinase c
PTEN	Phosphatase and TENsin homolog
RLC	Relative lymphocyte count
RNA	Ribonucleic acid
RTK	Receptor tyrosine kinase
TAM	Tumor-Associated Macrophages
TGFβ	Transforming Growth factor β
TIGIT	T-cell immunoreceptor with immunoglobulin and ITIM domains
TIL	Tumor-infiltrating lymphocytes
TLR	Toll-like receptor
TMB	Tumor mutational burden
TME	Tumor Microenvironment
Treg	Regulatory T-cell
WES	Whole exome sequencing
Bi	Bliography