Table 1.
Clinical profiles of 100 gastric cancer patients with low or high Tid1 expression in tumors.
| Characteristic | Tid1 Low Expression (0,1) (n = 30) | Tid1 High Expression (2,3) (n = 70) | p |
|---|---|---|---|
| Age (mean ± SD) | 67.80 ± 12.0 | 67.49 ± 12.6 | 0.908 |
| Gender | |||
| Male | 22 | 57 | |
| Female | 8 | 13 | 0.362 |
| Tumor size | |||
| <4 cm | 5 | 19 | |
| 4–8 cm | 17 | 38 | |
| >8 cm | 8 | 13 | 0.441 |
| Tumor location | |||
| Upper stomach | 5 | 15 | |
| Middle stomach | 15 | 25 | |
| Lower stomach | 10 | 27 | |
| Whole stomach | 0 | 3 | 0.548 |
| Cell grade | |||
| Poor differentiated | 18 | 35 | |
| Moderate differentiated | 11 | 34 | |
| Well differentiated | 1 | 1 | 0.381 |
| Gross appearance | |||
| Superficial type | 1 | 0 | |
| Borrmann type I & II | 7 | 25 | |
| Borrmann type III & IV | 22 | 45 | 0.177 |
| Stromal reaction type | |||
| Medullary type | 2 | 4 | |
| Intermediate type | 15 | 51 | |
| Scirrhous type | 13 | 15 | 0.058 |
| Lauren’s histology | |||
| Intestinal type | 8 | 27 | |
| Diffuse type | 14 | 19 | |
| Mixed type | 8 | 24 | 0.161 |
| Ming’s histology | |||
| Expanding | 2 | 7 | |
| Infiltrating | 28 | 63 | 0.720 |
| Lymphovascular invasion | |||
| No | 8 | 19 | |
| Yes | 22 | 51 | 0.133 |
| TNM pathological T category | |||
| T1 | 10 | 35 | |
| T2 | 7 | 15 | |
| T3 | 11 | 14 | |
| T4 | 2 | 6 | 0.289 |
| TNM pathological N category | |||
| N0 | 4 | 19 | |
| N1 | 5 | 20 | |
| N2 | 7 | 17 | |
| N3 | 14 | 14 | 0.041 * |
| TNM Stage | |||
| I | 1 | 9 | |
| II | 6 | 18 | |
| III | 23 | 43 | 0.274 |
| Overall survival rate (5 years) | 43.3% | 58.5% | 0.082 |
| Disease-free survival rate (5 years) | 36.7% | 57.1% | 0.008 * |
*, p < 0.05, statistical significance. #, American Joint Committee on Cancer (AJCC) Cancer Staging Manual, eighth edition, T category: T1, T2, T3, T4; N category: N0, N1, N2, N3.