Table 1.
Description of demographic characteristics, chronic polypharmacy, and chronic diseases at baseline according to age.
| Cohort n = 276,788 |
Middle-Aged 1 n = 159,243 |
Older Adults 2 n = 117,545 |
|
|---|---|---|---|
| Age, mean (sd) | 63.5 (10.2) | 54.1 (5.7) | 76.2 (14.2) |
| Sex, n (%) | |||
| Men | 131,275 (47.4) | 79,920 (50.2) | 51,355 (43.7) |
| Women | 145,513 (52.6) | 79,323 (49.8) | 66,190 (56.3) |
| Dead in 2016, n (%) | 4239 (1.5) | 663 (0.4) | 3576 (3.0) |
| Chronic polypharmacy n (% ± 95CI) | 36,500 (13.2 ± 0.2) | 8666 (5.4 ± 0.1) | 27,834 (23.7 ± 0.2) |
| Chronic hyperpolypharmacy n (% ± 95CI) | 3628 (1.3 ± 0.0) | 760 (0.5 ± 0.0) | 2868 (2.4 ± 0.0) |
| Most frequent chronic diseases 3 | |||
| Diabetes (type 1 or type 2) | 26,622 (9.6) | 9602 (6.0) | 17,020 (14.5) |
| Cancer or leukemia | 21,991 (8.0) | 6914 (4.3) | 15,077 (12.8) |
| Coronary artery disease | 13,248 (4.8) | 3566 (2.2) | 9682 (8.2) |
| Heart failure, arrhythmia or valvular heart disease | 12,437 (4.5) | 1908 (1.2) | 10,529 (9.0) |
| Psychiatric diseases | 10,108 (3.7) | 6301 (4.0) | 3807 (3.2) |
1 45–65 years old; 2 ≥65 years old; 3 defined as presenting with a prevalence >3% in the population; sd: standart deviation; 95CI: 95% confidence interval.