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. 2020 Nov 20;9(11):3726. doi: 10.3390/jcm9113726

Table 3.

Stepwise multivariate analysis.

AUC OR 95% CI β Coefficient p
Model 1—Basic medical history 0.814
Age 1.07 (1.04–1.10) 0.07 <0.001
Sex 0.71 (0.41–1.23) −0.34 0.22
Type of diabetes 2.99 (0.58–15.44) 1.10 0.19
Hypertension 2.94 (1.65–5.25) 1.09 <0.001
COPD 5.18 (0.94–28.43) 1.64 0.06
BMI (< or ≥ 40) 3.83 (1.20–12.22) 1.34 0.02
Model 2—Medical history and biological data at first examination 0.860
Age 1.07 (1.05–1.10) 0.07 <0.001
Sex 0.63 (0.35–1.14) −0.45 0.13
Type of diabetes (T2D vs T1D) 3.94 (0.68–22.9) 1.37 0.13
Hypertension 3.91 (2.08–7.35) 1.36 <0.001
BMI (< or ≥ 40) 4.39 (1.28–15.01) 1.48 0.02
CKD 28.1 (3.55–222.33) 3.34 0.002
Plasma glucose at admission 1.14 (1.07–1.22) 0.13 <0.001
Model 3—Medical history and long-term plasma glucose 0.830
Age 1.08 (1.04–1.12) 0.08 <0.001
Sex 0.62 (0.30–1.28) −0.47 0.2
Type of diabetes 3.83 (0.77–82.54) 2.08 0.08
Hypertension 3.82 (1.79–8.15) 1.34 <0.001
BMI (< or ≥ 40) 5.43 (0.81–36.45) 1.69 0.08
HbA1c 1.02 (0.80–1.29) 0.02 0.88
Plasma glucose at admission 1.12 (1.02–1.24) 0.18 0.02
Model 4—Medical history and antidiabetic treatment characteristics 0.825
Age 1.07 (1.03–1.09) 0.06 <0.001
Sex 0.67 (0.37–1.21) −0.41 0.18
Type of diabetes 24.51 (1.95–307.56) 3.20 0.01
Hypertension 2.68 (1.43–5.05) 0.99 0.002
BMI 4.72 (1.26–17.65) 1.55 0.02
Severe hypoglycemia 7.12 (0.55–91.58) 1.96 0.13
Insulin treatment 2.49 (1.20–5.17) 0.91 0.01
Model 5—Medical history and diabetes complications 0.831
Age 1.05 (1.03–1.08) 0.05 <0.001
Sex 0.83 (0.46–1.49) −0.19 0.53
Type of diabetes 4.24 (0.78–23) 1.44 0.09
Hypertension 2.29 (1.23–4.28) 0.83 0.01
BMI (< or ≥ 40) 4.07 (1.26–13.14) 1.40 0.02
Microangiopathy 2.11 (1.10–4.05) 0.74 0.02
Macroangiopathy 3.35 (1.50–7.52) 1.21 0.003
Model 6—Medical history and data at first examination 0.910
Age 1.03 (1.00–1.06) 0.03 0.03
Sex 0.92 (0.46–1.84) −0.08 0.82
Type of diabetes 45.34 (2.96–7033.84) 3.81 <0.001
Hypertension 3.51 (1.63–7.90) 1.25 <0.001
BMI (< or ≥ 40) 4.14 (0.92–21.17) 1.42 0.06
Peripheral oxygen saturation 0.58 (0.47–0.69) −0.54 <0.001
Insulin treatment 3.98 (1.82–9.02) 1.38 <0.001
Model 7- Clinical model simplified 0.910
Age 1.03 (1.01–1.06) 0.03 0.01
Type of diabetes 52.39 (3.42–8067.31) 3.95 <0.001
Hypertension 3.35 (1.66–7) 1.21 <0.001
Peripheral oxygen saturation 0.56 (0.46–0.66) −0.59 <0.001
Insulin treatment 3.70 (1.75–8.09) 1.31 <0.001

Age presented as continuous variable. CKD, chronic kidney disease.