Table 1.
Demographics, mitochondrial DNA (mtDNA) copy number, thiobarbituric acid reactive substances (TBARS), and thiols of Parkinson’s disease (PD) patients and non-PD controls.
| Variable | PD Patients | Non-PD Controls | p |
|---|---|---|---|
| (n = 725) | (n = 744) | ||
| Age, year (SD) | 67.1 (11.1) | 66.2 (9.4) | 0.109 |
| Male, number (%) | 396 (54.6) | 403 (54.2) | 0.861 |
| BMI, mean (SD) | 24.33 (3.64) | 24.97 (3.46) | <0.001 |
| Medical history | |||
| Hypertension (%) | 335 (46.2) | 411 (55.2) | <0.001 |
| Diabetes mellitus (%) | 139 (19.2) | 147 (19.8) | 0.787 |
| Smoking (%) | 120 (16.3) | 134 (18.0) | 0.511 |
| mtDNA copy number, log Delta Ct (SD) | 2.40 (0.17) | 2.46 (0.22) | <0.001 |
| TBARS, μmol/L (SD) | 1.59 (0.63) | 1.36 (0.76) | <0.001 |
| Thiols, μmol/L (SD) | 1.72 (0.42) | 1.79 (0.43) | <0.001 |