Table 5.
Risk Factors Associated with HFNC Failure in Multivariate Analysis
| Variable | Wald | Odds Ratios | 95% Confidence Interval | P |
|---|---|---|---|---|
| Univariate logistic regression | ||||
| Respiratory rate > 22 breaths per minute | 8.807 | 1.562 | 1.163–2.097 | 0.003 |
| PaCO2 (24 h) > 59 mmHg | 6.775 | 1.079 | 1.019–1.143 | 0.009 |
| PaCO2 (48 h) > 55 mmHg | 5.794 | 1.139 | 1.024–1.267 | 0.016 |
| Multivariate logistic regression | ||||
| PaCO2 (24 h) > 59 mmHg | 4.590 | 1.078 | 1.006–1.154 | 0.032 |
Abbreviations: HFNC, high-flow nasal cannula oxygen therapy; PaO2, partial pressure of oxygen; PaCO2, partial pressure of carbon dioxide.