Table 3.

The ROC Curve Assay of IGFBP7, CEA and a Combination of IGFBP7 and CEA

Variables	AUC (95% CI)	Sensitivity (%)	Specificity (%)
CRC vs NC
IGFBP7	0.815(0.754–0.877)	93.9	64.5
CEA	0.541(0.465–0.617)	78.3	29.9
IGFBP7+CEA	0.815(0.755–0.875)	99.1	57.9
Early stage CRC vs NC
IGFBP7	0.826(0.757–0.896)	95.8	64.5
CEA	0.545(0.421–0.669)	79.2	29.9
IGFBP7+CEA	0.829(0.758–0.899)	95.8	57.9

Abbreviations: AUC, area under the curve; 95% CI, 95% confidence interval; CRC, colorectal cancer; NC, normal controls.