(A) Gentiopicroside displayed a significant growth inhibition in GC cells with IC50 values. (B) Gentiopicroside suppressed HGC-27 cells proliferation significantly under the concentration of 0, 25, 50,100, 200, 400 μM with 24 h, 48 h and 72h incubation, respectively. (*P<0.05, **P<0.01).