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. 2020 Nov 24;12:12011–12020. doi: 10.2147/CMAR.S269572

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© 2020 Cai et al.

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Effects of SNHG1 and miR-140-5p on the PI3K/AKT pathway. (A) Effects of SNHG1 on the PI3K/AKT pathway-related protein levels in transfected KNS-81 cells. (B) Effects of SNHG1 on the PI3K/AKT pathway-related protein levels in transfected KALS-1 cells, and its correspond protein profiling. (C) Effects of miR-140-5p on the PI3K/AKT pathway-related protein levels in transfected KNS-81 cells. (D) Effects of miR-140-5p on the PI3K/AKT pathway-related protein levels in transfected KALS-1 cells, and its corresponding protein profiling.

Notes: **Indicates P<0.01 vs the si-NC group; ^##Indicates P<0.01 vs the SNHG1 group.

Abbreviations: SNHG1, small nucleolar RNA host gene 1; miR, microRNA; NC, negative control; si, short interfering; PI3K, phosphatidylinositol 3 kinase; AKT, protein kinase B; p-AKT, phosphorylated-protein kinase B; AMPK, AMP-activated protein kinase; p-AMPK, phosphorylated-AMP-activated protein kinase.