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. 2020 Nov 23;13:12055–12066. doi: 10.2147/OTT.S282053

Figure 6.

Figure 6

RAB14 was a direct downstream target of miR-338-3p. (A) Venn diagram of the predicted target genes in five databases (left), and schematic representation of the RAB14 3′-UTR containing the binding site for miR-338-3p (right). (B) The dual-luciferase reporter assay. (C) Western blot showed that miR-338-3p inhibited the expression of RAB14 protein. (D and E) EdU assay indicated that the knockdown of RAB14 significantly inhibited cell proliferation. (F) Transwell assay for migration. (G) Transwell assay for invasion. (H and I) RAB14, E-cadherin, and N-cadherin were detected by Western blot. *p < 0.05 and **p < 0.01.