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Reduction of c-Fos expression in spinal cord by intra-RVM microinjection of SB203580. The immunofluorescence of c-Fos in the spinal dorsal horn. (A) Sham group; (B) CIPN-DMSO group; (C) CIPN-SB203580 group; (D) Fos positive neurons count (* vs Sham group, P < 0.05, # vs CIPN-DMSO group, P < 0.05, n = 4 per group). Bar: 100 μm.
