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Table 6.

Intravenous to oral analgesic/sedation conversions.

Current intravenous agent	Oral alternative	Dose calculation
Fentanyl (mcg/kg/h)	Morphine (mg/kg/dose)^a	Multiply hourly fentanyl dose by 0.1. Administer as morphine every 4 h.
Fentanyl (mcg/kg/h)	Methadone (mg/kg/dose)^a	Multiply hourly fentanyl dose by 0.05–0.1. Administer as methadone every 6 h.
Midazolam (mg/kg/h)	Lorazepam (mg/kg/dose)^a	Multiply hourly midazolam dose by 0.5–1. Administer as lorazepam every 6 h.
Dexmedetomidine (mcg/kg/h)	Clonidine (mcg/kg/dose)^a	Multiply hourly dexmedetomidine dose by 5. Administer as clonidine every 4 h.

^aDose calculations result in weight-based dose. Multiply by dosing weight to convert from mg/kg/dose to mg/dose.