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. 2020 Nov 23;8(11):1840. doi: 10.3390/microorganisms8111840

Figure 4.

Figure 4

Mechanisms of immunopathogenesis induced by SARS-CoV-2 in humans (A), and feline coronavirus (CoV) in cats (B). The figure was created using icons from biorender.com (accessed 18 September 2020). Abbreviations: Ab—antibody; ACE2—angiotensin-converting enzyme 2; ADE—antibody-dependent enhancement; DAMPs—damage-associated molecular patterns; fAPN—feline aminopeptidase N; FcγR—Fc gamma receptor; FECoV—feline enteric coronavirus; FIPV—feline infectious peritonitis virus; PAMPs—pathogen-associated molecular patterns; RAS—renin–angiotensin system; TMPRSS2—transmembrane protease—serine 2.