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. 2020 Nov 20;9(11):3741. doi: 10.3390/jcm9113741

Figure 4.

Figure 4

Inhibitory action of the IL-13/IL-4‒JAK‒STAT6/STAT3 axis on the AHR axis. The IL-13/IL-4‒JAK‒STAT6/STAT3 axis inhibits the AHR-mediated transcription of FLG, LOR, and IVL. The IL-13/IL-4‒JAK‒STAT6/STAT3 axis also inhibits the cytoplasmic-to-nuclear translocation of OVOL1.