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. 2020 Nov 23;13(22):5303. doi: 10.3390/ma13225303

Table 2.

Potential clinical applications of dental SCs in regenerative dentistry.

Type of SCs Regenerative Dental Applications References
DPSCs Mandibular bone defects regeneration, scaffold-based dentin–pulp repair, dentin–pulp tissue regeneration with inflamed pulp, periodontal regeneration, neural tissue regeneration, muscle regeneration, angiogenesis induction, craniofacial skeletal repair Zhou et al. [11]
Zakrzewski et al. [17]
Berebichez-Fridman et al. [18]
Hollands et al. [22]
Tsutsui [23]
Sharpe [24]
Khazaei et al. [28]
Chalisserry et al. [30]
Somani et al. [31]
Yang et al. [142]
Chatzistavrou et al. [144]
Bakopoulou et al. [145]
Tatullo et al. [146]
Potdar et al. [147]
Davila et al. [148]
Gronthos et al. [149]
Beltrão-Braga et al. [150]
Verma et al. [151]
Almushayt et al. [152]
Yoshida et al. [153]
Aydin et al. [154]
Graziano et al. [155]
PDLSCs Tooth root regeneration, periodontal tissue regeneration (cementum, PDL), bone regeneration Zhou et al. [11]
Zakrzewski et al. [17]
Liu et al. [20]
Somani et al. [31]
Verma et al. [151]
Aydin et al. [154]
Kitagaki et al. [156]
Hynes et al. [157]
Han et al. [158]
Maeda et al. [159]
Gay et al. [160]
Kim et al. [161]
SCAPs Bone regeneration, tooth root regeneration, dentin–pulp repair, neural regeneration and repair, periodontal regeneration, angiogenesis, tooth regeneration Zhou et al. [11]
Liu et al. [20]
Kang et al. [25]
Khazaei et al. [28]
Somani et al. [31]
Bakopoulou et al. [145]
Verma et al. [151]
Aydin et al. [154]
Schneider et al. [162]
Nada et al. [163]
Miller et al. [164]
Wongwatanasanti et al. [165]
DFCs Bone defects, tooth root regeneration, periodontal tissue regeneration, neural tissue regeneration, enhancement of bone regeneration on titanium implant surfaces in humans Zhou et al. [11]
Zakrzewski et al. [17]
Liu et al. [20]
Chalisserry et al. [30]
Somani et al. [31]
Yang et al. [142]
Verma et al. [151]
Aydin et al. [154]
Zhang et al. [166]
Shoi et al. [167]
Rezai-Rad et al. [168]
Honda et al. [169]
TGSCs Bone repair and cartilage regeneration Zhou et al. [11]
Chalisserry et al. [30]
Verma et al. [151]
Aydin et al. [154]
Caracappa et al. [170]
Yalvaç et al. [171]
Yalvaç et al. [172]
Doğan et al. [173]
SHEDs Critical-sized craniofacial bone defect regeneration, scaffold-based dentin–pulp regeneration, neural and blood vessel regeneration, tooth root regeneration, tubular dentin Zhou et al. [11]
Liu et al. [20]
Sharpe [24]
Somani et al. [31]
Verma et al. [151]
Aydin et al. [154]
Jeon et al. [174]
Araújo et al. [175]
Ma et al. [176]
Kunimatsu et al. [177]
Ching et al. [178]
Miura et al. [179]
Martinez Saez et al. [180]
Annibali et al. [181]
Arora et al. [182]
ABMSCs Bone defects, periodontal regeneration Zhou et al. [11]
Liu et al. [20]
Verma et al. [151]
Aydin et al. [154]
Caracappa et al. [170]
Mason et al. [183]
Liu et al. [184]
Pekovits et al. [185]
Matsubara et al. [186]
Park et al. [187]
Lim et al. [188]
Khazaei et al. [189]
GMSCs Neural regeneration, periodontal regeneration, cartilage, bone,
muscle, oral mucositis,
improving the regeneration of craniofacial bone
Liu et al. [20]
Chalisserry et al. [30]
Grawish [33]
Verma et al. [151]
Aydin et al. [154]
Caracappa et al. [170]
Zhang et al. [190]
Tomar et al. [191]
Tang et al. [192]
Wang et al. [193]
Marynka-Kalmani et al. [194]
Zhang et al. [195]