Table 1.

Comparison of type 1 and type 2 diabetes mellitus.

Feature	T1DM	T2DM
body weight at the time of diagnosis	within the normal range or underweight	overweight or obese
cause of the disease	insulin deficiency as a result of β-cells damage	insulin resistance
presence of antibodies	anti-GAD, ICA, IA2, IAA, ZnT8	not found
disease onset	acute with accompanying diabetic ketoacidosis	mild onset
basic pharmacotherapy	insulin	initially metformin and other orally administered medications, in some cases insulin
Does the occurrence of the disease depend on a patient’s lifestyle?	no	yes

anti-GAD: anti-glutamic acid decarboxylase; ICA: islet cell antibodies; IA2: islet antigen 2; IAA: insulin autoantibodies; ZnT8: zinc transporter 8.