Table 2.
Descriptive information of MPM patients. Median survival (365 days) was used as cut-off value to stratify patients in high and low survivors.
Categorical Variable | Level | Low OS (n = 79) | High OS (n = 80) | ||
N | % | N | % | ||
Centre | Casale | 50 | 63.3 | 46 | 57.5 |
Torino | 29 | 36.7 | 34 | 42.5 | |
Gender | Males | 59 | 74.7 | 50 | 62.5 |
Females | 20 | 25.3 | 30 | 37.5 | |
Smoke | Current | 20 | 26.3 | 8 | 10.3 |
Former | 24 | 31.6 | 29 | 37.2 | |
Never | 32 | 42.1 | 41 | 52.6 | |
Histotype | Epithelioid | 44 | 55.7 | 61 | 76.3 |
Sarcomatoid | 14 | 17.7 | 2 | 2.5 | |
Biphasic | 17 | 21.5 | 11 | 13.8 | |
Undefined | 2 | 2.5 | 1 | 1.3 | |
Not known | 2 | 2.5 | 5 | 6.3 | |
Continuous Variable | Level | Low OS | High OS | ||
Mean | SD | Mean | SD | ||
Overall Survival (days) | 198.7 | 101.6 | 957.8 | 698.7 | |
Age (years) | 67.7 | 12.4 | 67.5 | 9.6 | |
Asbestos Exp. (norm) | 1.4 | 1.5 | 1.5 | 1.9 | |
CD8T (%) | 2.9 | 4.5 | 3 | 3.4 | |
CD4T (%) | 6.8 | 5.3 | 8.8 | 5.4 | |
Natural Killer (%) | 4.9 | 4.9 | 6.3 | 4.1 | |
B cell (%) | 6.1 | 2.8 | 6.4 | 2.7 | |
Monocytes (%) | 8.1 | 4.1 | 7.6 | 4.4 | |
Granulocytes (%) | 75 | 13 | 72 | 10 |
Asbestos exposure (occupational, environmental, and domestic) was normalized considering frequency, duration, and intensity.