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. 2020 Nov 22;9(11):3760. doi: 10.3390/jcm9113760

Table 3.

Results of 15N/14N and 13C/12C isotope ratio estimation.

Delta Air p Value * Delta PDB p Value **
Tumour 15N/14N Min 8.10 p < 0.01 13C/12C Min −24.36 p < 0.00001
15N/14N Max 10.88 p < 0.001 13C/12C Max −19.99 p = 0.0514515
15N/14N Mean +/− SD 8.93 ± 0.58 p < 0.0001 13C/12C Mean +/− SD −22.21 ± 0.89 p < 0.0001
15N/14N Median 8.71 p < 0.001 13C/12C Median −22.33 p < 0.001
Margin 15N/14N Min 8.19 13C/12C Min −24.93 p < 0.00001
15N/14N Max 11.38 p < 0.001 13C/12C Max −21.54 p = 0.0514515
15N/14N Mean +/− SD 9.53 ± 0.64 p < 0.0001 13C/12C Mean +/− SD −23.36± 0.92 p < 0.0001
15N/14N Median 9.49 p < 0.001 13C/12C Median −23.43 p < 0.001
Healthy Tissue 15N/14N Min 8.35 p < 0.01 13C/12C Min −25.26 p < 0.00001
15N/14N Max 10.78 p < 0.001 13C/12C Max −21.07
15N/14N Mean +/− SD 9.84 ± 0.61 p < 0.0001 13C/12C Mean +/− SD −23.68 ± 1.18 p < 0.0001
15N/14N Median 9.86 <0.001 13C/12C Median −24.32 p < 0.001

* The maximum, mean and median values differed statistically between: (1) healthy tissue and tumour (2) margin and tumour. In addition, statistically significant differences in the minimum of delta Air were observed between: (1) healthy tissue and tumour (p < 0.01). ** The comparison of mean, standard deviation and median values of healthy tissue and tumour as well as margin samples and tumour tissues revealed a statistical significance. The correlations between maximum values of margin and tumour samples were also observed (p value = 0.0514515). In addition, statistically significant differences in the minimum of delta PDB in all tissues were observed.