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Cytotoxicity of crude fractional extracts and pure compounds from C. comosa to cancer cell lines. K562, KG-1a, HL-60, A549, and MCF-7 cells were treated with (A) ethyl acetate fraction (F-EtOAc), (B) compound 1, (C) hexane fraction (F-Hex), or (D) compound 2 for 48 h. Cell viability was determined using the MTT assay. Each point represents the mean ± standard deviation (SD) of three independent experiments, each performed in triplicate.
