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. 2020 Nov 22;21(22):8833. doi: 10.3390/ijms21228833

Figure 6.

Figure 6

Identification of putative miRNA candidates for FAM83A knockdown through a bioinformatics approach. (A) Identification of miRNA candidates to regulate FAM83A expression. Expression levels of the 13 miRNAs and FAM83A in 458 LUAD and 46 normal tissues are shown as heat maps. Candidate genes whose expression was significantly increased (p < 0.01) or reduced in lung cancer tissues compared with in adjacent normal tissues are labeled in red and green, respectively. (B) Pearson correlation analysis of miR-1-3p and FAM83A expression in 185 patients with LUAD. (C) TCGA database analysis of miR-1-3p expression in lung cancer. (D) Kaplan-Meier survival curves showing the effects of miR-1-3p expression on overall survival of patients with LUAD.