Table 1.
Thyroid carcinoma cell lines used in this study.
| Cell Line | Histological Type | Medium | Source | Mutation Identified 1 |
|---|---|---|---|---|
| BCPAP | PTC | RPMI 1640 medium, supplemented with 5% FBS | DSMZ Cat No. ACC 273 | BRAF V600E, TP53 D258Y, TERT c.-124C>T and c.-125C>T |
| TPC1 | PTC | RPMI 1640 medium, supplemented with 10% FBS | João R. Maciel, UNIFESP, SP, Brazil | RET/PTC1, TERT c.-124C>T |
| FTC133 | FTC | DMEM and Ham’s F12 (1:1) medium, supplemented with 10% FBS | ECACC cat no. 94060901 | NF1 C167*, PTEN R130*, TP53 R273H, TERT c.-124C>T, RB1*, MSH6* |
| FTC236 | FTC | DMEM and Ham’s F12 (1:1) medium, supplemented with 10% FBS, 1 mU/mL TSH, and 10 µg/mL insulin | ECACC cat. no. 06030202 | PTEN R130*, TP53 R273H, TERT c.-124C>T, RB1*, MSH6* and others |
| FTC238 | FTC | DMEM and Ham’s F12 (1:1) medium, supplemented with 10% FBS | ECACC cat no. 94060902 | PTEN R130*, TP53 R273H, TERT c.-124C>T, RB1*, MSH6* |
| WRO | FTC | DMEM medium, supplemented with 10% FBS | Alfredo Fusco, Università degli Studi di Napoli Federico II, Italy | TP53 P223L, BRAF wild type, TERT promoter wild type |
| TT | MTC | F-12K medium, supplemented with 10% FBS | ECACC cat no. 92050721 | RET C634W |
1 Mutations characterized by Landa et al. (2019) [11]. PTC, papillary thyroid carcinoma; FTC; follicular thyroid carcinoma; MTC, medullary thyroid carcinoma.