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. 2020 Nov 22;12(11):732. doi: 10.3390/toxins12110732

Figure 2.

Figure 2

Effect of OTA expositions on the glutathione reductase (GR) activity in the kidney cortex. (A) GR activity of kidney samples in case of single oral dose (24 h) OTA treatment. The applied OTA doses did not change significantly the GR activity. (B) GR activity of kidney samples in case of repeated daily oral dose (72 h) OTA treatment. The applied OTA doses did not change significantly the GR activity. (C) GR activity of kidney samples in case of repeated daily oral dose (21 days) OTA treatment. The applied OTA dose did not change the GR activity significantly. Abbreviations: MMS: methyl-methanesulfonate-treatment group; OTA 1 and OTA 10: 1 and 10 mg/kg bw ochratoxin A treatment in the single oral dose (24 h) and repeated daily oral dose (72 h) groups; OTA 0.5: 0.5 mg/kg bw ochratoxin A treatment in the repeated daily oral dose (21 days) group. Mean ± S.D. Data were analyzed by one-way ANOVA and Tukey’s post hoc test. * p < 0.05 vs. vehicle.