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Overall gene expression changes induced by oxidized low-density lipoproteins (OxLDL) or LDL treatment in ARPE-19 cells. (a) Total number of treatment-specific and common genes differentially expressed following exposure of the cells to OxLDL (2 and 4 h) and LDL (4 h) (fold change ≥ 1.5, FDR < 5%). (b) Number of significantly up- and down-regulated genes following exposure to OxLDL (2 and 4 h) and LDL (4 h) (fold change ≥ 1.5, FDR < 5%).
