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. 2020 Nov 22;21(22):8828. doi: 10.3390/ijms21228828

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(A) The binding site of inositol phosphate with HDAC3-SMRT complex. The inositol phosphate is shown as a stick model. Adaptedwith permission from Watson 2012 [94]. (B) Relative position of the allosteric site and binding rail on HDAC2. Adapted with permission from Zhou 2017 [96].