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. Author manuscript; available in PMC: 2020 Nov 29.

Published in final edited form as: Adv Anat Pathol. 2020 May;27(3):114–163. doi: 10.1097/PAP.0000000000000256

Image 9. — SOX10 Expression by Triple-Negative Breast Cancer: (A) Triple-negative breast cancers can be negative for (B) GATA-3, and, even when they are positive, expression is often weak, overlapping with the “non-specific” expression seen in other tumor types. (C) SOX10 is expressed by 60% of triple-negative cancers, typically in diffuse, strong fashion, which I have found to be complementary to GATA-3 in securing this diagnosis.

Image 9. — SOX10 Expression by Triple-Negative Breast Cancer: (A) Triple-negative breast cancers can be negative for (B) GATA-3, and, even when they are positive, expression is often weak, overlapping with the “non-specific” expression seen in other tumor types. (C) SOX10 is expressed by 60% of triple-negative cancers, typically in diffuse, strong fashion, which I have found to be complementary to GATA-3 in securing this diagnosis.