Table 1.
Characteristics of the study population
| Characteristic | Total (n=582) | Control (n=532) | Borderline-high mean corpuscular volume (n=50) | P-value |
|---|---|---|---|---|
| Age (y) | 47.8±11.7 | 47.3±11.7 | 52.5±10.5 | 0.002 |
| Body mass index (kg/m2) | 23.8±2.9 | 23.8±2.9 | 23.5±2.7 | 0.586 |
| Male gender | 331 (56.9) | 295 (55.5) | 36 (72.0) | 0.023 |
| Current smoker | 132 (22.7) | 120 (22.6) | 12 (24.0) | 0.815 |
| Alcohol consumption | 420 (71.2) | 379 (71.2) | 41 (82.0) | 0.104 |
| Regular exercise | 344 (59.1) | 311 (58.5) | 33 (66.0) | 0.299 |
| Systolic blood pressure (mm Hg) | 119.5±15.2 | 119.4±15.3 | 120.8±14.4 | 0.527 |
| Diastolic blood pressure (mm Hg) | 73.1±11.9 | 72.9±12.0 | 75.5±10.9 | 0.145 |
| Fasting plasma glucose (mg/dL) | 96.2±18.5 | 96.1±18.9 | 96.7±14.3 | 0.784 |
| Triglyceride (mg/dL) | 113.7±94.7 | 112.5±90.2 | 127.1±134.0 | 0.453 |
| High-density lipoprotein cholesterol (mg/dL) | 48.1±12.6 | 47.9±12.5 | 50.1±13.9 | 0.226 |
| White blood cells (×103 cell/μL) | 5.5±1.4 | 5.5±1.3 | 5.5±1.6 | 0.903 |
| C-reactive protein (mg/L) | 0.6±0.6 | 0.6±0.6 | 0.6±0.7 | 0.694 |
| γ-glutamyltransferase (U/L) | 24.4±16.0 | 23.7±15.3 | 32.3±20.6 | 0.005 |
| Uric acid (mg/dL) | 5.2±1.4 | 5.2±1.4 | 5.4±1.3 | 0.198 |
| Hemoglobin (d/dL) | 14.6±1.4 | 14.6±1.4 | 14.9±1.2 | 0.197 |
| Hypertension medication | 73 (12.5) | 70 (13.2) | 3 (6.0) | 0.144 |
| Diabetes medication | 24 (4.1) | 23 (4.3) | 1 (2.0) | 0.429 |
Values are presented as mean±standard deviation or number (%), unless otherwise stated.