Fig. 2.

Network of evidence for adults and adolescents.

Legend: Circles (nodes) in the diagrams represent individual treatments, lines between circles represent availability of head-to-head evidence between two treatments, and the numbers on the lines are the number of RCTs informing each head-to-head comparison. Blue: NNRTIs; Green: Protease inhibitors; Orange: Integrase inhibitors. ATV/r: ritonavir-boosted atazanavir; BIC: bictegravir; DRV/r: ritonavir-boosted darunavir; DTG: dolutegravir; EFV: efavirenz; EVG/c: Elvitegravir/cobicistat; LPV/r: ritonavir-boosted lopinavir; NVP: nevirapine; RAL: raltegravir; RPV: rilpivirine.