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. 2020 Oct 22;22:1154–1163. doi: 10.1016/j.omtn.2020.10.024

Figure 2.

Figure 2

Overexpression of GAS5 Suppressed the Expression of miR-222 and miR-21, but Activated the Expression of p27 and MMP-9

(A) GAS5 suppressed the expression of miR-222 in HepG2 and LX2 cells. (B) GAS5 activated the expression of p27 mRNA in HepG2 and LX2 cells. (C) GAS5 suppressed the expression of miR-21 in HepG2 and LX2 cells. (D) GAS5 activated the expression of MMP-9 mRNA in HepG2 and LX2 cells. (E) Western blot analysis indicated that GAS5 activated the expression of p27 protein in HepG2 and LX2 cells. (F) Western blot analysis indicated that GAS5 activated the expression of MMP-9 protein in HepG2 and LX2 cells. ∗p < 0.05 versus Lenti group.