Table 3.
Characteristics of donor and recipients with most common cancers
| Donors | Recipients | |||
|---|---|---|---|---|
| Lymphoma | 38 (20) | 48 (21) | ||
| Donor type |
D = 18 (47) L = 3 (8) NA = 17 (45) |
Localization |
Graft = 32 (66) Metastasizing = 9 (19) NA = 7 (15) |
|
| Cause of death |
Cerebral hemorrhage = 3 (8) Head trauma = 7 (18) Other = 3 (8) NA = 25 (66) |
Treatment |
Nx only = 8 (17) Nx-RTx = 1 (2) Nx-other = 13 (27) CHT-RT-IT only = 1 (2) NA = 25 (52) |
|
| Donor study |
Yes, with imaging or biopsy = 3 (8) Yes, without imaging = 3 (8) NA = 32 (84) |
Immunosuppression |
Withdrawal = 18 (38) NA = 30 (62) |
|
| Autopsy was performed in 3 cases; 2 donors with cancer history | ||||
| Renal cell carcinoma | 37 (20) | 42 (18) | ||
| Donor type |
D = 27 (73) L = 8 (22) NA = 2 (5) |
Localization |
Graft = 28 (67) Metastasizing = 11 (26) NA = 3 (7) |
|
| Cause of death |
Cerebral hemorrhage = 11 (30) Head trauma = 3 (8) NA = 23 (62) |
Treatment |
Nx only = 31 (74) Nx-RTx = 1 (2) Nx-other = 5 (11) CHT-RT-IT only = 1 (2) No/supportive = 3 (7) NA = 1 (2) |
|
| Donor study |
Yes, with imaging or biopsy = 6 (16) Yes, without imaging = 2 (5) NA = 29 (79) |
Immunosuppression |
Withdrawal = 11 (26) Mantained = 11 (26) NA = 20 (48) |
|
| Autopsy was performed in 2 cases; 1 donor with cancer history | ||||
| Melanoma | 30 (16) | 40 (17) | ||
| Donor type |
D = 28 (93) L = 2 (7) |
Localization |
Graft = 5 (12) Metastasizing = 33 (83) NA = 2 (5) |
|
| Cause of death |
Cerebral hemorrhage = 13 (43) Head trauma = 1 (3) CNS malignancy = 2 (7) Other malignancy = 1 (3) NA = 23 (62) |
Treatment |
Nx only = 12 (30) Nx-RTx = 1 (2) Nx-other = 15 (38) No/supportive = 9 (23) NA = 3 (7) |
|
| Donor study |
None = 2 (7) Yes, with imaging or biopsy = 1 (3) Yes, without imaging = 8 (27) NA = 19 (63) |
Immunosuppression |
Withdrawal = 23 (58) Mantained = 1 (2) NA = 16 (40) |
|
| Autopsy was performed in 6 cases; 8 donors with cancer history | ||||
| Lung cancer | 12 (6) | 13 (6) | ||
| Donor type |
D = 11 (92) NA = 1 (8) |
Localization |
Graft = 4 (31) Metastasizing = 8 (61) NA = 1 (8) |
|
| Cause of death |
Head trauma = 1 (8) Other malignancy = 2 (17) Other = 3 (25) NA = 6 (50) |
Treatment |
Nx only = 5 (39) Nx-other = 1 (8) CHT-RT-IT only = 2 (15) No/supportive = 3 (23) NA = 2 (15) |
|
| Donor study |
Yes, without imaging = 7 (58) NA = 5 (42) |
Immunosuppression |
Withdrawal = 4 (31) Mantained = 1 (8) NA = 8 (61) |
|
| Autopsy was performed in 7 cases; 5 donors with cancer history | ||||
| Breast cancer | 4 (2) | 5 (2) | ||
| Donor type |
D = 3 (75) L = 1 (25) |
Localization |
Graft = 2 (40) Metastasizing = 3 (60) |
|
| Cause of death |
Cerebral hemorrhage = 1 (25) Other malignancy = 1 (25) Other = 1 (25) NA = 1 (25) |
Treatment |
Nx-other = 1 (20) CHT-RT-IT only = 1 (20) No/supportive = 3 (60) |
|
| Donor study |
Yes, with imaging or biopsy = 1 (25) Yes, without imaging = 2 (50) NA = 1 (25) |
Immunosuppression |
Withdrawal = 1 (20) Mantained = 1 (20) NA = 3 (60) |
|
| Autopsy was performed in 2 cases; 2 donors with cancer history | ||||
CHT chemotherapy, CNS central nervous system, D deceased donor, F female, IT immunotherapy, L, living donor, M male, NA not available, Nx explant nephrectomy, RT radiotherapy, RTx retransplant, SD standard deviation. All data are in absolute number and percentage in parentheses