Table 1.
Test articles, mesh classification, source materials, and explant time points
| Mesh | Manufacturer | Class | Composition | Time point (weeks) | Animals per time point |
|---|---|---|---|---|---|
| OviTex® PGA 1S | Developed, designed and manufactured by: Aroa Biosurgery Limited and TELA Bio, Inc | Reinforced biologic | Decellularized ovine forestomach matrix ECM embroidered with polyglycolic acid (PGA) | 4, 12, 24 | 3 |
| OviTex® PP 1S | Reinforced biologic | Decellularized ovine forestomach matrix ECM embroidered with polypropylene (PP) | 4, 12, 24 | 3 | |
| Phasix™ | CR Bard (Davol) | Resorbable synthetic | Poly-4-hydroxybutyrate (P4HB) and polyglycolic acid (PGA) | 4, 12, 24 | 3 |
| Ventralight ST™ | CR Bard (Davol) | Permanent synthetic | Polypropylene and polyglycolic acid (PGA) with sodium hyaluronate (HA) carboxymethylcellulose (CMC) and polyethylene glycol (PEG) based hydrogel barrier | 4, 12, 24 | 3 |
| Physiomesh™a | Ethicon | Permanent synthetic | Polypropylene laminated between polyglecaprone-25 films bond w/polydioxanone film | 4, 12, 24 | 2 |
| Strattice™ Firm | LifeCell (now Allergan) | Biologic | Decellularized porcine dermal ECM | 4, 12, 24 | 5 |
| SurgiMend 1.0™ | TEI Biosciences (now Integra) | Biologic | Decellularized fetal bovine dermal ECM | 4, 12 weeks | 3 |
| Gentrix® Surgical Matrix Plus | ACell | Biologic | Decellularized porcine urinary bladder ECM | 4, 12 | 2 |
| Zenapro™a | Cook Medical | Hybrid biologic | Decellularized porcine small intestinal submucosa ECM and polypropylene | 4, 12 | 3 |
| Total animals | 73 | ||||
aNo longer in distribution