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. 2020 Nov 16;11:582345. doi: 10.3389/fpsyt.2020.582345

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Copyright © 2020 Panariello, Cellini, Speciani, De Ronchi and Atti.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The RAAS cascade. Simplified picture of the Central RAAS pathway depicting the main steps leading to the synthesis of Angiotensin (1-7) which, in turn, binds and activates with the highest affinity the MasR.