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. 2020 Nov 25;15:9431–9445. doi: 10.2147/IJN.S266006

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© 2020 Li et al.

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Illustration scheme for UCNP-RGD (A) and in vivo up-conversion luminescence imaging of subcutaneous U87MG tumor (left hind leg) and MCF-7 tumor (right hind leg) after intravenous injection of UCNP-RGD conjugate over a 24-hour period (B). (a, d, g) bright field, (b, e, h) up-conversion images, (c, f, i) overlay of the corresponding bright field images with the up-conversion ones. (a–c), (d–f), and (g–i) are taken at 1, 4 and 24 hours postinjection, respectively.

Note: Copyright ©2009. American Chemical Society. Reproduced from Xiong L, Chen Z, Tian Q, et al. High contrast upconversion luminescence targeted imaging in vivo using peptide-labeled nanophosphors. Anal Chem. 2009;81: 8687–8694.⁶³