Table 1.

Summary of UCNPs-Based Nanosystem for Cancer Imaging and Phototheranostics

UCNPs	Coating	Cargo/Drug	Imaging Modality Type Modality	Therapy Type	Cell	Refs.
NaGdF4:Yb, Tm@NaGdF4:Yb	ZnFe2O4	DOX	OMI, MRI, CT	PDT, CDT, chemotherapy	HeLa	[68]
NaGdF4:Yb, Er@NaGdF4:Yb, Nd	–	–	–	PDT	4T1	[74]
NaLuF4:Yb, Er@NaLuF4	Carbon	–	–	PTT	HeLa	[75]
NaYF4:Yb, Er@CaF2:Yb(80%), Er(2%)@CaF2	–	Ce6	OMI	PDT	HepG2	[91]
NaYF4:Yb, Er@NaYF4:Yb, Nd	SiO2	DOX	OMI, CT	PTT, chemotherapy	HeLa	[92]
NaYF4:Yb, Tm@NaGdF4:Yb	TiO2	–	MRI, CT	PDT	HeLa	[94]
NaYF4:Er, Yb	PLGA/Span 80/Cremophor A25	Rose bengal	–	PDT	MeWo/Me-45	[95]
NaYF4:Er, Yb	PEG	Rose bengal	–	–	–	[96]
NaGdF4:Yb, Er @ NaGdF4:Yb	MnO2/SiO2/PEG	DOX, Ce6	MRI, CT	Chemotherapy, PDT	HeLa, U14	[90]
NaYF4:Yb, Er, Gd@NaYF4	Lysine	Rose bengal	–	PDT	SK-BR-3	[97]
NaYF4: Yb, Tm	Cell membrane	GOX	–	PTT, starvation therapy	4T1	[103]