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. 2020 Nov 25;13:12181–12193. doi: 10.2147/OTT.S262896

Figure 7.

Figure 7

miR-325-3p regulates GITR expression in vitro. (A) GITR expression in miR-325-3p overexpression MKN45 cell line. (B) GITR expression in miR-325-3p knock down MKN45 cell line. (C) Dual luciferase reporter gene assay for miR-325-3p and GITR. (D) Rescue experiments for CCK-8 in MKN45. Group: NC, miR-325-3p overexpression, GITR overexpression, miR-325-3p overexpression + GITR overexpression. (E) Rescue experiments for caspase 3/7 apoptosis in MKN45. Group: NC, miR-325-3p overexpression, GITR overexpression, miR-325-3p overexpression + GITR overexpression. *indicates that P value<0.05.