Table 1.
Significantly upregulated and downregulated genes (FC≥ 2) upon exposure of B. longum subsp. longum GT15 to TNFα compared to controls by RNAseq.
| Gene no | Annotation | Log2 (FC) |
|---|---|---|
| BLGT_RS00625 | Hsp20/alpha crystalline family protein | 5,10 |
| BLGT_RS00855 | Hypothetical protein | 2,18 |
| BLGT_RS01135 | PEGA domain-containing protein | 2,37 |
| BLGT_RS01265 | Uridylyltransferase | 2,02 |
| BLGT_RS01310 | Sugar ABC transporter substrate-binding protein | 2,20 |
| BLGT_RS02915 | ABC transporter substrate-binding protein | 2,04 |
| BLGT_RS02940 | LacI family DNA-binding transcriptional regulator | 2,32 |
| BLGT_RS02975 | Sugar ABC transporter substrate-binding protein | 2,87 |
| BLGT_RS03150 | LamB/YcsF family protein | 2,13 |
| BLGT_RS03250 | Zinc ABC transporter solute-binding protein | 3,19 |
| BLGT_RS03890 | CarD family transcriptional regulator | −2,18 |
| BLGT_RS04345 | YccF domain-containing protein | −2,15 |
| BLGT_RS04350 | Hypothetical protein | −2,17 |
| BLGT_RS04520 | DUF4418 family protein | −2,24 |
| BLGT_RS04525 | ABC transporter permease | −2,12 |
| BLGT_RS07100 | SPFH domain-containing protein | 2,02 |
| BLGT_RS07650 | DedA family protein | −2,02 |
| BLGT_RS07990 | AmmeMemoRadiSam system protein B | 2,03 |
| BLGT_RS08190 | Sugar ABC transporter substrate-binding protein | 2,10 |
| BLGT_RS08205 | ROK family glucokinase | −2,08 |
| BLGT_RS08485 | Sugar ABC transporter permease | 2,04 |
| BLGT_RS08615 | Circularly permuted type 2 ATP-grasp protein | 2,78 |
| BLGT_RS08920 | tRNA-Met | −2,11 |
| BLGT_RS09910 | Signal recognition particle sRNA small type | 2,16 |
| BLGT_RS09925 | Hypothetical protein | −2,25 |