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. 2020 Nov 16;11:583740. doi: 10.3389/fimmu.2020.583740

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Copyright © 2020 Dong, Yin, Meng, Xu, Liu, Wang and Xu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Infection with F. columnare in rainbow trout. (A) The culture plates of olfactory organ from control fish (left) and 1 day infected fish (right). (B) localzation of F. cloumnare in olfactory organ of control fish and infected fish at 1, 3, and 4 dpi. Data are representative of three independent experiments. (C) Heat map demonstrated quantitative real-time PCR (qPCR) results of F. columnare in olfactory organ of infected fish versus control fish measured at 1, 2, 4, 7, 14, 21, 28, and 75 dpi (n = 6 fish per group). NC, nasal cavity; OE, olfactory epithelium; LP, lamina propria. Scale bar, 100 μm.