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. 2020 Nov 16;10:593381. doi: 10.3389/fonc.2020.593381

Table 1.

Comparisons of the mean dosimetric parameters (across the five cross-validation folds) between the baseline high-resolution anisotropic analytical algorithm (AAA) dose (with a 1 mm grid) and the low-resolution AAA dose (with 3 or 5 mm grids)/predicted high-resolution AAA dose in the planning target volume (PTV), bladder, and rectum.

ROI Parameters AAA
Baseline(1 mm grid) 3 mm grid Prediction AAA 3 model 5 mm grid Prediction AAA 5 model
PTV Mean dose (Gy) 73.3 (4.0) 73.0 (4.1) 73.3 (4.0) 72.6 (4.1) 73.3 (4.0)
Max. dose (Gy) 79.7 (3.0) 77.4 (3.7) 79.3 (3.4) 76.2 (4.1) 78.6 (3.8)
Min. dose (Gy) 61.4 (5.0) 61.6 (5.3) 61.5 (4.9) 62.0 (5.1) 62.9 (3.9)
V95% (%) 98.9 (0.6) 97.9 (0.9) 99.0 (0.6) 93.7 (3.0) 98.9 (0.6)
CI 1.08 (0.03) 1.04 (0.02) 1.08 (0.03) 0.97 (0.04) 1.07 (0.03)
HI 0.09 (0.01) 0.10 (0.01) 0.09 (0.01) 0.12 (0.02) 0.09 (0.01)
Bladder Mean dose (Gy) 17.1 (11.0) 17.2 (11.1) 17.1 (11.0) 17.4 (11.1) 17.1 (11.0)
Max. dose (Gy) 78.7 (3.2) 76.7 (3.8) 78.1 (3.4) 75.4 (4.2) 77.1 (3.6)
Min. dose (Gy) 1.1 (1.0) 1.1 (1.0) 1.0 (1.0) 1.2 (1.3) 1.1 (1.1)
V70% (%) 12.9 (11.6) 12.9 (11.5) 12.9 (11.5) 13.0 (11.5) 13.1 (11.6)
V50% (%) 19.4 (15.9) 19.7 (16.0) 19.4 (15.9) 20.0 (16.2) 19.6 (16.0)
V30% (%) 27.6 (19.6) 28.0 (19.7) 27.6 (19.6) 28.6 (20.0) 27.8 (19.6)
Rectum Mean dose (Gy) 28.8 (8.5) 28.7 (8.5) 28.8 (8.5) 28.6 (8.4) 28.7 (8.5)
Max. dose (Gy) 76.5 (3.5) 75.2 (3.7) 76.0 (3.6) 73.9 (3.9) 75.0 (3.8)
Min. dose (Gy) 1.0 (0.7) 1.1 (0.7) 1.0 (0.6) 1.2 (0.7) 1.1 (0.7)
V70% (%) 15.4 (7.6) 15.3 (7.5) 15.4 (7.6) 15.3 (7.5) 15.3 (7.6)
V50% (%) 32.7 (15.1) 32.4 (15.0) 32.7 (15.2) 32.2 (14.6) 32.6 (15.0)
V30% (%) 61.6 (16.0) 61.4 (16.0) 61.5 (16.0) 61.2 (16.0) 61.3 (16.0)

The Vn% indicates the percentage of the volume irradiated by n% of the prescription dose. Values expressed in bold are not statistically significant (p-value of >0.05). The standard deviations are indicated in parentheses.

ROI, region of interest; HI, homogeneity index; CI, conformity index; AAA, anisotropic analytical algorithm.